| Phenyl salicylate[1] | |
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Phenyl 2-hydroxybenzoate |
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Other names
Salol |
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| Identifiers | |
| CAS number | 118-55-8 |
| PubChem | 8361 |
| ChEMBL | CHEMBL1339216 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C13H10O3 |
| Molar mass | 214.22 g/mol |
| Appearance | White solid |
| Density | 1.25 g/cm3 |
| Melting point |
41.5 °C |
| Boiling point |
173 °C (at 12 mmHg) |
| Solubility in water | 1 g/6670 mL |
| (verify) (what is: /?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Phenyl salicylate, or salol, is a chemical substance, introduced in 1886 by Marceli Nencki of Basel. It can be created by heating salicylic acid with phenol. Once used in sunscreens, phenyl salicylate is now used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes.[1] It is also used frequently in school laboratory demonstrations on how cooling rates affect crystal size in igneous rocks.
In the salol reaction, phenyl salicylate reacts with o-toluidine in 1,2,4-trichlorobenzene at elevated temperatures to the corresponding amide o-Salicylotoluide [2]. Salicylamides are one type of drug.
It has been used as an antiseptic[3] based on the antibacterial activity upon hydrolysis in the small intestine.
It acts as a mild analgesic.[4] It has the ATC code G04BX12.
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